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Arteries and veins have different types of endothelium but it is unclear how these molecular and functional differences are specified during development.

To understand more, Ludwig Oxford’s Alice Neal and colleagues from Sarah De Val’s group studied venous development in mice and zebrafish. They found that BMP signalling is required for transcriptional activation of the key venous regulator Ephb4 and subsequent establishment of venous blood vessels. This work, published in Nature Communications, therefore identifies a new potential target for anti-angiogenic therapy to reduce tumour growth.

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International Women's Day within Ludwig Oxford

The 8th March annually celebrates Women's achievements and we are delighted to celebrate the women researchers, students and staff within Ludwig Oxford