We are hiring new talent here at the Target Discovery Institute, Nuffield Department of Medicine to work under the supervision of Associate Professor Chunxiao Song. The Song research group aims to decode the chemical modifications of our genome, transcriptome, and proteome in human health and disease – cancer in particular – and translating this information into diagnostic and therapeutic opportunities that ultimately benefit patients. Recently, we developed a novel sequencing method for the most abundant RNA modification pseudouridine (bioRxiv 2024.2001.2008.574649, Nat. Methods accepted). We are seeking a highly motivated Postdoctoral Research Scientist with experience in RNA biology to lead various projects to uncover the role of pseudouridine and pseudouridine synthases (PUS) in cancer, and explore the potential clinical application of pseudouridine in the circulating cell-free RNA for cancer diagnostics.
Within this role, you will be responsible for managing your own academic research and administrative activities. This involves small scale project management, coordinating multiple aspects of work to meet deadlines. You will be tasked with adapting existing and developing new scientific techniques and experimental protocols as well as testing hypotheses and analysing scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will also be collaborating in the preparation of scientific reports and journal articles and occasionally present papers and posters. Finally, you will act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.
It is essential that you hold a relevant PhD/DPhil (or close to completion) in Molecular Biology/ Biochemistry/ Biology/ Chemistry or a related scientific subject. You will have experience in epitranscriptomics or RNA biology and experience of actively collaborating in the development of research articles for publication, in a relevant subject (such as epitranscriptomics or RNA biology). You will also have a strong skill set in standard Molecular Biology/Biochemistry/Cell Biology techniques and experience of communicating results clearly and logically as part of a diverse research team.
Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.
This position is offered full time on a fixed term contract for 30 September 2026 and is funded by Ludwig. Only applications received before 12 midday on 12 August 2024 will be considered. Please quote 171490 on all correspondence.
This position is offered full time on a fixed term contract for 30 September 2026 and is funded by Ludwig. Only applications received before 12 midday on 12 August 2024 will be considered. Please quote 171490 on all correspondence.