{ "items": [ "\n\n
\n \n 22 April 2021\n \n
\n\n \n\n \n\n \n \n \n \n Moura Alves\n \n \n\n \n\n\n
\n \n\n \n \n \nDr Pedro Moura Alves described how the aryl hydrocarbon receptor senses bacteria to fine-tune the body\u2019s response to infection
\n \n\n\n \n 7 April 2021\n \n
\n\n \n\n \n\n \n \n \n \n Ratcliffe\n \n \n\n \n\n\n
\n \n\n \n \n \nActivation of hypoxia inducible factors (HIFs) by either hypoxia or drug treatment inhibits SARS-CoV-2 entry and replication in lung epithelial cells, raising the potential of using clinically licensed HIF activators to prevent and/or treat COVID-19.
\n \n\n\n \n 12 March 2021\n \n
\n\n \n\n \n\n \n \n \n \n Shi\n \n \n\n \n\n\n
\n \n\n \n \n \nProfessor Yang Shi\u2019s group uses combination therapy to eradicate tumours that previously responded poorly to immunotherapy
\n \n\n\n \n 4 March 2021\n \n
\n\n \n\n \n\n \n \n \n \n Boccellato\n \n \n\n \n\n\n
\n \n\n \n \n \nA new review from the Boccellato lab describes the experimental models for studying the stages from Helicobacter pylori infection to carcinogenesis.
\n \n\n\n \n 3 March 2021\n \n
\n\n \n\n \n\n \n \n \n \n Moura Alves\n \n \n\n \n\n\n
\n \n\n \n \n \nDr Pedro Moura Alves has developed a microscale thermophoresis-based approach for rapidly and robustly analysing aryl hydrocarbon receptor interactions.
\n \n\n\n \n 2 March 2021\n \n
\n\n \n\n \n\n \n \n \n \n Schuster-B\u00f6ckler\n \n \n\n \n\n\n
\n \n\n \n \n \nDr Benjamin Schuster-B\u00f6ckler wins funding to develop algorithms that can identify both genetic variation and DNA methylation from the same sequencing data, with applications in biomedical research and detection of diseases such as cancer.
\n \n\n\n \n 17 February 2021\n \n
\n\n \n \n \n\n \n \n \nGermline and somatic variants in the p53 pathway cooperate to influence cancer risk, progression and response to therapy.
\n \n\n\n \n 11 February 2021\n \n
\n\n \n\n \n\n \n \n \n \n Lu\n \n \n\n \n\n\n
\n \n\n \n \n \nLudwig Oxford Director Professor Xin Lu features in this showcase of women in diverse roles across Oxford\u2019s Medical Sciences Division.
\n \n\n\n \n 9 February 2021\n \n
\n\n \n\n \n\n \n \n \n \n De Val\n \n \n\n \n\n\n
\n \n\n \n \n \nProfessor Sarah De Val, Dr Alice Neal and Dr Svanhild Nornes investigate the role of ETS factors in blood vessel specification.
\n \n\n\n \n 4 February 2021\n \n
\n\n \n\n \n\n \n \n \n \n Gyrd-Hansen\n \n \n\n \n\n\n
\n \n\n \n \n \nProfessor Mads Gyrd-Hansen reviews the current knowledge about this important post-translational modification.
\n \n\n\n \n 27 January 2021\n \n
\n\n \n\n \n\n \n \n \n \n Shi\n \n \n\n \n\n\n
\n \n\n \n \n \nProfessor Yang Shi uncovers a new role for RNA methylation and the RNA methyltransferase METTL3 in the maintenance of heterochromatin
\n \n\n\n \n 27 January 2021\n \n
\n\n \n\n \n\n \n \n \n \n Song\n \n \n\n \n\n\n
\n \n\n \n \n \nDr Chunxiao Song\u2019s team have expanded their suite of bisulphite-free DNA modification sequencing methods to specifically and directly detect each of the four modifications made to the DNA base cytosine
\n \n\n\n \n 27 January 2021\n \n
\n\n \n \n \n\n \n \n \nLudwig Oxford welcomes this leading international figure in the field of cancer epigenetics
\n \n\n\n \n 4 January 2021\n \n
\n\n \n\n \n\n \n \n \n \n Lu\n \n \n\n \n\n\n
\n \n\n \n \n \nThe drug arsenic trioxide can restore the structure and function of some p53 tumour suppressor mutants, with potential as a future personalised cancer treatment strategy.
\n \n\n\n \n 8 December 2020\n \n
\n\n \n\n \n\n \n \n \n \n Shi\n \n \n\n \n\n\n
\n \n\n \n \n \nLudwig Oxford\u2019s newest recruit is interviewed in the latest edition of the Ludwig Link.
\n \n\n\n \n 30 November 2020\n \n
\n\n \n\n \n\n \n \n \n \n Lu\n \n \n\n \n\n\n
\n \n\n \n \n \nAn interdisciplinary collaboration generates an advanced model of the human gastrointestinal tract with broad applications for disease research and regenerative medicine.
\n \n\n\n \n 25 November 2020\n \n
\n\n \n\n \n\n \n \n \n \n Lu\n \n \n \n \n Rittscher\n \n \n\n \n\n\n
\n \n\n \n \n \nA multidisciplinary team of researchers has developed a deep-learning framework for improving endoscopy to aid cancer detection.
\n \n\n\n \n 16 November 2020\n \n
\n\n \n \n \n\n \n \n \nLudwig Oxford Director Professor Xin Lu features in this edition of the FEBS Journal.
\n \n\n\n \n 11 November 2020\n \n
\n\n \n \n \n\n \n \n \nScenic Biotech, co-founded by former Ludwig Oxford group leader Sebastian Nijman, collaborates with Roche group member Genentech in a $375m deal.
\n \n\n\n \n 30 October 2020\n \n
\n\n \n\n \n\n \n \n \n \n Song\n \n \n\n \n\n\n
\n \n\n \n \n \nOxford spin-out Base Genomics is acquired by early cancer detection company Exact Sciences.
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