The new Oxford-developed artificial intelligence tool PathProfiler automates the quality control of large retrospective pathology image datasets to increase their usability in downstream research.
The Pearl clinical study will recruit 3000 patients with high-risk conditions for liver cancer with the aim of detecting liver cancer earlier as part of the Cancer Research UK-funded DeLIVER programme led by Ludwig adjunct Professor Ellie Barnes.
A project aimed at tackling heart failure led by Associate Professor Sarah De Val is to be funded by the 2022 TCS London Marathon with the British Heart Foundation as its Charity of the Year.
A novel immunotherapeutic called VTP-600, based on Ludwig Oxford\u2019s Benoit Van den Eynde\u2019s preclinical research, is being tested in patients for the first time.
Professor Yang Shi\u2019s laboratory uncovers an important role for the chromatin regulator LSD1 in T cell exhaustion and demonstrates that LSD1 inhibition in mice increases the durability of responses to immune checkpoint blockade therapy.
Anneliese Dodds, MP for Oxford East & Chair of the Labour Party, visited the University of Oxford to learn more about the impactful cancer research happening across departments, including Ludwig Oxford.
Interactions between transcription factors and the chromatin environment provide barriers controlling cell differentiation, according to research by Professor Yang Shi and colleagues.
Dr Tammie Bishop\u2019s and Professor Sir Peter Ratcliffe\u2019s groups shed light on the developmental origins of inherited cancers with mutations in the HIF pathway.
Ludwig Oxford\u2019s Professor Colin Goding and Sao Paulo\u2019s Professor Silvya Stuchi Maria-Engler show that TOP1 is involved in melanoma progression and adaptive resistance to treatment.
A new publication from Benoit Van den Eynde's group has shown that a viral vector cancer vaccine generates effective anti-tumour immune responses and, in combination with immunotherapy, decreases tumour size and increases survival rates in mouse models.
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