The E3 ligase APC/C Cdh1 promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth
Cao J., Dai X., Wan L., Wang H., Zhang J., Goff PS., Sviderskaya EV., Xuan Z., Xu Z., Xu X., Hinds P., Flaherty KT., Faller DV., Goding CR., Wang Y., Wei W., Cui R.
Loss of a ubiquitin ligase promotes melanoma growth.