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Publications

Inosine pranobex enhances human NK cell cytotoxicity by inducing metabolic activation and NKG2D ligand expression.

McCarthy MT. et al, (2020), European journal of immunology, 50, 130 - 137

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta cells

Vergari E. et al, (2020), Nature Metabolism, 2, 32 - 40

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Vergari E. et al, (2019), Nature Communications, 10

Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production

Knudsen JG. et al, (2019), Cell Metabolism, 29, 430 - 442.e4

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies

Fielding JW. et al, (2018), The Journal of Physiology, 596, 4393 - 4412

Purine nucleotide metabolism regulates expression of human MICA.

O'Callaghan C. et al, (2018), JOURNAL OF IMMUNOLOGY, 200

Purine nucleotide metabolism regulates expression of the human immune ligand MICA

McCarthy MT. et al, (2018), Journal of Biological Chemistry, 293, 3913 - 3924

Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes

Manuel AM. et al, (2017), Antioxidants & Redox Signaling, 27, 1281 - 1296

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes

Adam J. et al, (2017), Cell Reports, 20, 3135 - 3148

Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance

Nijhuis A. et al, (2017), Human Molecular Genetics, 26, 1552 - 1564

Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome

Llamas-Velasco M. et al, (2016), The American Journal of Dermatopathology, 38, 887 - 891

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

Bardella C. et al, (2016), Cancer Cell, 30, 578 - 594

Increased Expression of the Diabetes GeneSOX4Reduces Insulin Secretion by Impaired Fusion Pore Expansion

Collins SC. et al, (2016), Diabetes, 65, 1952 - 1961

The Succinated Proteome of FH-Mutant Tumours

Yang M. et al, (2014), Metabolites, 4, 640 - 654

Rare insights into cancer biology

Adam J. et al, (2014), Oncogene, 33, 2547 - 2556

Rare insights into cancer biology

Adam J. et al, (2014), Oncogene, 33, 2547 - 2556

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

Singleton RS. et al, (2014), Proceedings of the National Academy of Sciences, 111, 4031 - 4036

A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

Adam J. et al, (2013), Cell Reports, 3, 1440 - 1448

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

Ternette N. et al, (2013), Cell Reports, 3, 689 - 700

Cells Lacking the Fumarase Tumor Suppressor Are Protected from Apoptosis through a Hypoxia-Inducible Factor-Independent, AMPK-Dependent Mechanism

Bardella C. et al, (2012), Molecular and Cellular Biology, 32, 3081 - 3094

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