Dorota Szumska-Bilska

Post-doctoral Fellow

My research focuses on the transcriptional regulation of genes crucial for the development of mammalian vascular system.

I have many years of experience in mouse embryogenesis. In the De Val lab, my work includes generating and analysing mouse models of normal and pathological vascular specification, growth and homeostasis. In particular, I am developing a pipeline for imaging and analysing our enhancer:reporter transgenic embryos on a variety of different mutant backgrounds using High Resolution Episcopic Microscopy (HREM).

Recent publications

Pcsk5 is required in the early cranio-cardiac mesoderm for heart development
Journal article

Szumska D. et al, (2017), BMC Developmental Biology, 17
A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)
Journal article

Geyer SH. et al, (2017), Journal of Anatomy, 230, 710 - 719
ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome
Journal article

Zak J. et al, (2016), Cell Death & Differentiation, 23, 1973 - 1984
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
Journal article

Wilson R. et al, (2016), Wellcome Open Research, 1, 1 - 1
Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs
Journal article

Grijzenhout A. et al, (2016), Development, 143, 2716 - 2723

More publications