Cytosine methylation is the most common epigenetic change in human DNA and it is crucial for the correct regulation of gene expression. 5-methylcytosine (5mC) is mutated more frequently than its unmethylated counterpart, which is important in immune system development, evolution, but also in cancer formation and progression. In my DPhil, I am investigating the relationship between 5mC and transversion mutations in several human cancers.
I completed my BSc in Human Genetics at the University of Nottingham and my MRes in Cancer Informatics at the Imperial College London. In my Masters’ thesis, I investigated the impact of PTEN loss on microRNA landscape in prostate cancer, and the proximal mutational effects of 5mC in various cancers. I also did two laboratory-based internships in the Institute of Human Genetics (Poznan, Poland) and in the Brook Lab (University of Nottingham), where I worked on gene knockouts to study Myotonic Dystrophy.
I am also a team member of the Polonium Foundation, where we connect the polish scientific diaspora around the world. When I am not at work, you can find me organising various events with the Polonium Foundation, or somewhere at a climbing wall.