My research focuses on how our body responds to invading pathogens in the first line of defence. When a cell senses a pathogen, two different responses can be mounted: an inflammatory response and cell death. Whereas an inflammatory response produces cytokines and pathogen-limiting factors, the cell’s suicide machinery acts as a back-up in case the inflammatory response is not successful or not sufficient, to ensure that the pathogen is not taking advantage of its environment to survive.
My current work focuses on a type of proinflammatory cell death called necroptosis. Specifically, I’m looking at how essential components of this pathway coordinate the proinflammatory response and cell death.
I graduated from Peking University, Beijing, with BSc in Life Sciences before joining the Ludwig Institute for PhD in Professor Mads Gyrd-Hansen’s group.