I am interested in understanding detailed molecular mechanisms of cancer biology and designing new therapeutic approaches for cancer treatment.
iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.
Chen S. et al, (2019), Proceedings of the National Academy of Sciences of the United States of America, 116, 17470 - 17479
A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway
Lu M. et al, (2014), Cell, 157, 1130 - 1145