Senior Research Officer
My research focuses on the use of zebrafish to study regulatory pathways that control new blood vessel growth (angiogenesis). Formation of new blood vessels is necessary for cancer development to provide oxygen and nutrients to the tumour. Understanding the intricate interplay of regulatory pathways that governs new blood vessel growth will help in finding new therapies for cancer.
PhD. Biochemistry, University of Tromso, Norway, 1998.
MSc. Centre for Biotechnology, University of Bergen, Norway, 1991.
BSc. University of Bergen, Norway, 1988.
Venous identity requires BMP signalling through ALK3.
Neal A. et al, (2019), Nature communications, 10
MEF2 transcription factors are key regulators of sprouting angiogenesis
Sacilotto N. et al, (2016), Genes & Development, 30, 2297 - 2309
Pro-survival p53 target genes have evolved clusters of interacting polymorphic response elements that can affect cancer risk
Zhang P. et al, (2016), European Journal of Cancer, 61, S110 - S110
Enhancer Directs Arterial-Specific Expression via RBPJ-Mediated Venous Repression
Becker PW. et al, (2016), Arteriosclerosis, Thrombosis, and Vascular Biology, 36, 1209 - 1219
Robust homeostasis of Presenilin1 protein levels by transcript regulation
Newman M. et al, (2012), Neuroscience Letters, 519, 14 - 19