Contact information
Svanhild Nornes
Senior Research Officer
Research interests
My research focuses on the use of zebrafish to study regulatory pathways that control new blood vessel growth (angiogenesis). Formation of new blood vessels is necessary for cancer development to provide oxygen and nutrients to the tumour. Understanding the intricate interplay of regulatory pathways that governs new blood vessel growth will help in finding new therapies for cancer.
Background
PhD. Biochemistry, University of Tromso, Norway, 1998.
MSc. Centre for Biotechnology, University of Bergen, Norway, 1991.
BSc. University of Bergen, Norway, 1988.
Recent publications
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ETS factors are required but not sufficient for specific patterns of enhancer activity in different endothelial subtypes
Journal article
Neal A. et al, (2021), Developmental Biology, 473, 1 - 14
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Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response.
Journal article
Zhang P. et al, (2021), Cancer research, 81, 1667 - 1680
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Venous identity requires BMP signalling through ALK3.
Journal article
Neal A. et al, (2019), Nature communications, 10
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MEF2 transcription factors are key regulators of sprouting angiogenesis
Journal article
Sacilotto N. et al, (2016), Genes & Development, 30, 2297 - 2309
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Pro-survival p53 target genes have evolved clusters of interacting polymorphic response elements that can affect cancer risk
Conference paper
Zhang P. et al, (2016), European Journal of Cancer, 61, S110 - S110