Senior Research Officer
My research focuses on the use of zebrafish to study regulatory pathways that control new blood vessel growth (angiogenesis). Formation of new blood vessels is necessary for cancer development to provide oxygen and nutrients to the tumour. Understanding the intricate interplay of regulatory pathways that governs new blood vessel growth will help in finding new therapies for cancer.
PhD. Biochemistry, University of Tromso, Norway, 1998.
MSc. Centre for Biotechnology, University of Bergen, Norway, 1991.
BSc. University of Bergen, Norway, 1988.
ETS factors are required but not sufficient for specific patterns of enhancer activity in different endothelial subtypes
Neal A. et al, (2021), Developmental Biology, 473, 1 - 14
Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response.
Zhang P. et al, (2021), Cancer research
Venous identity requires BMP signalling through ALK3.
Neal A. et al, (2019), Nature communications, 10
MEF2 transcription factors are key regulators of sprouting angiogenesis
Sacilotto N. et al, (2016), Genes & Development, 30, 2297 - 2309
Pro-survival p53 target genes have evolved clusters of interacting polymorphic response elements that can affect cancer risk
Zhang P. et al, (2016), European Journal of Cancer, 61, S110 - S110