I joined Professor Mads Gyrd-Hansen’s group as a post-doctoral researcher in 2019. My research focuses on inflammation. Chronic inflammation causes cell death and damage to our tissues. These tissues release DNA-damaging chemicals that can lead to cancer. Therefore, by limiting inflammation we can reduce the risk of developing cancer. One way of reducing inflammation is by targeting ubiquitination, a mechanism of protein modification. The aim of my project is to understand how ubiquitin regulates inflammation and cell death, which can guide the discovery of druggable targets against chronic inflammation.
I did my PhD at the Institute of Microbiology and Infection, University of Birmingham. During my PhD I studied the relationship between antibiotic resistance and virulence in Salmonella Typhimurium. Prior to my PhD, I trained as a Chemist Bacteriologist Parasitologist (undergraduate degree) at the National School of Biological Sciences in Mexico. To obtain my degree, I worked on a research project at the Infectology Department of the Children’s Hospital of Mexico Federico Gomez. This project was on quorum sensing, a bacterial communication system that regulates the expression of virulence factors.
Author Correction: Multidrug efflux pumps: structure, function and regulation.
Du D. et al, (2018), Nature reviews. Microbiology, 16
Multidrug efflux pumps: structure, function and regulation.
Du D. et al, (2018), Nature reviews. Microbiology, 16, 523 - 539
Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium.
Wang-Kan X. et al, (2017), mBio, 8