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Researchers from Dr Tammie Bishop’s and Prof Sir Peter Ratcliffe’s laboratories show that an anti-cancer HIF inhibitor impairs the normal ventilatory response to low oxygen.
Toward Integration of Molecular Measures and Artificial Intelligence-Based Assessments With Clinical End Points in Inflammatory Bowel Disease
Journal article
Reinisch W. et al, (2026), Gastroenterology, 170, 686 - 703
Therapeutic manipulation and spatial quantification of the tumor microenvironment in colorectal cancer.
Journal article
Mulholland-Illingworth EJ. et al, (2026), iScience, 29
Hypoxic regulation of chromatin and gene transcription
Journal article
Kindrick JD. et al, (2026), Communications Biology
Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS–chemokine–myeloid axis
Journal article
Beernaert B. et al, (2026), Science Advances, 12
The Role of Fibroblast–Epithelial Cross-Talk on the Distribution of Distinct Fibroblast Phenotypes in the Intestinal Crypt
Journal article
Atkinson G. et al, (2026), Bulletin of Mathematical Biology, 88
The RNA-binding protein SRSF3 controls epicardial formation by regulating splicing and proliferation
Journal article
Lupu I-E. et al, (2026), Development, 153
comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders
Journal article
Shen Y. et al, (2026), Cell Stem Cell, 33, 421 - 437.e7
Risk Factors of Metabolic Dysfunction-associated Steatotic Liver Disease in a Cohort of Patients With Chronic Hepatitis B
Journal article
Kalafateli M. et al, (2026), Clinical Gastroenterology and Hepatology, 24, 701 - 712.e8
Mathematical modelling and analysis of unsteady poroelastohydrodynamics for an in-vivo type solid tumour.
Journal article
Alam M. et al, (2026), Journal of mathematical biology, 92
Rapid and durable recovery of immune effector cells in myelofibrosis patients treated with momelotinib.
Journal article
Makker J. et al, (2026), Haematologica, 111, 1096 - 1099
Topological model selection: a case-study in tumour-induced angiogenesis.
Journal article
McDonald RA. et al, (2026), Bioinformatics (Oxford, England)
Self-supervised Monocular Depth and Pose Estimation for Endoscopy with Latent Priors.
Journal article
Xu Z. et al, (2026), IEEE transactions on medical imaging, PP
Discrete genetic effects of VHL and PBRM1 inactivation co-operate to disrupt epithelial homeostasis and promote ccRCC
Preprint
Kurlekar S. et al, (2026)
When, which and how to switch: Navigating JAK inhibitors in myelofibrosis
Journal article
O'Sullivan J. et al, (2026), British Journal of Haematology, 208, 437 - 441
ACE2 inhibition ELISA is an effective surrogate for SARS-CoV-2 live virus neutralisation
Journal article
Tipton T. et al, (2026), Vaccine, 72, 128123 - 128123
Response to Comments on ‘Hepatitis B Virus ( HBV ) Treatment Eligibility in the UK : Retrospective Longitudinal Cohort Data to Explore the Impact of Changes in Clinical Guidelines’
Journal article
Campbell C. et al, (2026), Journal of Viral Hepatitis, 33
Restoring Function to a Variant of p53 in Solid Tumors.
Journal article
Lu X., (2026), The New England journal of medicine, 394, 922 - 925
Chemo-prAIdict Breast: A deep learning solution for predicting residual disease on biopsies of breast cancer patients treated with neoadjuvant chemotherapy.
Journal article
Valderrama NF. et al, (2026), European journal of cancer (Oxford, England : 1990), 234
JAK2V617F reprograms Hypoxia Inducible Factor-1 to induce a non-canonical hypoxia regulon in myeloproliferative neoplasms.
Journal article
Kealy D. et al, (2026), Leukemia
Ancestry and somatic profile indicate acral melanoma origin and prognosis.
Journal article
Basurto-Lozada P. et al, (2026), Nature