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Insights into mTORC1 regulation

Using quantitative genetic screens, researchers from Professor Sebastian Nijman’s lab learn more about the regulation of a key growth control pathway.

Collaboration with Magdalen College outreach to run remote work experience

Public Engagement

Ludwig Oxford's Dr Tammie Bishop organised a week of work experience for fifteen year 12 students in collaboration with the Magdalen Outreach Team.

Using machine-learning approaches to identify blood cancer types

Improving the accuracy of myeloproliferative neoplasm typing at diagnosis will enable better selection of treatments for improved patient outcomes.

Targeting the aryl hydrocarbon receptor

Dr Pedro Moura Alves secures funding to screen for drugs that regulate aryl hydrocarbon receptor (AHR) activity.

Funding success for Ludwig Oxford early career researchers

Drs Michael McClellan, Marketa Tomkova and Yurena Vivas-Garcia win CRUK Oxford Centre Development Fund awards to pump-prime their research.

Uncovering roles for ubiquitin ligases

Mapping the protein-protein interactions of ubiquitin ligases in the endoplasmic reticulum has revealed a new complex that modulates innate immune signalling.

Linking cancer risk and anthropometric traits

Heritable variants in common cancer genes link anthropometric features like height with cancer risk.

Ludwig Oxford welcomes cancer epigenetics researcher Yang Shi

Yang Shi has been appointed a Member of the Ludwig Oxford Branch to continue his research into chromatin, RNA modifications and cancer.

Insights into the two faces of AMPK, a key nutrient sensor

Professor Colin Goding and colleagues reveal that a distinct metabolic environment in colon cancer cells allows AMPK to be activated by glucose to drive cancer proliferation, with implications for AMPK-targeting cancer drugs.

Debunking assumptions

Researchers from Colin Goding’s lab demonstrate that weakening a transcription factor’s DNA binding affinity in vitro paradoxically increases its function in vivo.

Dr Benjamin Schuster-Böckler elected as a Fellow of Parks College

Ludwig Oxford’s Benjamin Schuster-Böckler is one of 31 Official Fellows in this new Oxford college.

Ludwig Oxford-developed DNA methylation technology forms the basis of new startup company

Biotechnology company, Base Genomics, has launched based on Dr Chunxiao Song’s innovative TAPS technology.

Funding for COVID-19 research

Dr Francesco Boccellato is awarded money from Oxford’s COVID-19 Research Response Fund

Ludwig Oxford technology holds great promise for a multi-cancer blood test

Ongoing Oxford research aims to improve the sensitivity of cancer blood tests with the goal of earlier detection for a variety of cancers.

Professor Sir Peter Ratcliffe elected as an AACR Academy Fellow

Sir Peter joins the ranks of the American Association for Cancer Research’s finest scientists.

Prof Xin Lu honoured by the Royal Society

Ludwig Oxford Branch Director Xin Lu has been elected as a Fellow of the Royal Society for her contributions to cancer biology.

Investigating the genetic risk of adrenocortical carcinoma

Bond lab researchers study the genetic factors associated with the age-dependent incidence of adrenocortical carcinoma.

Adaptation of TAPS for long-read DNA methylation and hydroxymethylation sequencing

Chunxiao Song’s technology can now be used to measure DNA modifications on much longer sections of DNA.

Crowd-sourcing approach to improve endoscopic detection of cancer

Evaluating the algorithms developed to detect a range of imaging artefacts in endoscopy.

Peter Ratcliffe’s Life Scientific

Nobel Prize winner Professor Sir Peter Ratcliffe talks to Jim Al-Khalili on BBC Radio 4.

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