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UNIQ summer school 2021

Kriaucionis Lu Public Engagement Van den Eynde

Three Ludwig Oxford volunteers participate at the 2021 Oncology UNIQ summer school

Ludwig Oxford and Oxford University welcome Professor Stefan Constantinescu

Constantinescu

Professor Stefan Constantinescu joins Ludwig Oxford to expand his research programme in cancer epigenetics.

Understanding the role of BRN2 in melanoma

Goding

A study from Professor Colin Goding’s group gives insight into the function of the BRN2 transcription factor in promoting melanoma initiation and metastasis.

AI endoscopy enables 3D surface measurements of pre-cancerous condition in oesophagus

Lu Rittscher

Clinicians and engineers in Oxford have begun using artificial intelligence alongside endoscopy to get more accurate readings of the pre-cancerous condition Barrett’s oesophagus and so determine patients most at risk of developing cancer.

Combination treatment approach for acute myeloid leukaemia

Shi

Professor Yang Shi’s group demonstrates that combining drugs targeting epigenetic and metabolic pathways can overcome the arrest of white blood cell differentiation in this blood cancer.

Reporter assay to identify dormant cells

Goding

Professor Colin Goding’s lab collaborate with colleagues in Germany to develop a new method to measure stem cell dormancy.

CRUK Oxford Centre Development Fund awarded to Dr Linna Zhou

Lu

Ludwig Oxford’s Dr Linna Zhou will investigate the role of the nervous system in cancer progression using engineered gastrointestinal tissues.

Artificial intelligence tool for streamlining pathology workflow

Rittscher

A multidisciplinary team, comprising Ludwig Oxford’s Professor Jens Rittscher with Andrea Chatrian, Dr Richard Colling, Professor Clare Verrill and colleagues, develops an algorithm for automated requesting of additional investigation in diagnostically uncertain prostate biopsies.

Cancer immunologist Lieping Chen joins Ludwig Oxford as a Visiting Professor

Ludwig Oxford are delighted to welcome this acclaimed scientist to the Branch and the Oxford community.

Ludwig-Oxford Symposium on Cancer Early Detection and Epigenetics – a recap

Rittscher Shi Song

On 28-29th April 2021, we heard the latest developments from international leaders in these fields from the University of Oxford, Ludwig Cancer Research and beyond.

Understanding cell organisation in the human stomach

Boccellato

Dr Francesco Boccellato investigates how growth factors influence differentiation and patterning in human gastric glands.

New method for cost-effective genome-wide DNA methylation analysis

Song

Dr Chunxiao Song’s team build on its TAPS method to develop an alternative to costly whole-genome sequencing for the detection of DNA methylation.

Ludwig Oxford researcher presents at the Oxford Immunology Symposium

Moura Alves

Dr Pedro Moura Alves described how the aryl hydrocarbon receptor senses bacteria to fine-tune the body’s response to infection

HIFs inhibit SARS-CoV-2 infection of lung epithelial cells

Ratcliffe

Activation of hypoxia inducible factors (HIFs) by either hypoxia or drug treatment inhibits SARS-CoV-2 entry and replication in lung epithelial cells, raising the potential of using clinically licensed HIF activators to prevent and/or treat COVID-19.

Improving immunotherapy

Shi

Professor Yang Shi’s group uses combination therapy to eradicate tumours that previously responded poorly to immunotherapy

Investigating infection-associated stomach cancer

Boccellato

A new review from the Boccellato lab describes the experimental models for studying the stages from Helicobacter pylori infection to carcinogenesis.

New method for studying AhR interactions

Moura Alves

Dr Pedro Moura Alves has developed a microscale thermophoresis-based approach for rapidly and robustly analysing aryl hydrocarbon receptor interactions.

Developing a system to simultaneously detect genetic and epigenetic information

Schuster-Böckler

Dr Benjamin Schuster-Böckler wins funding to develop algorithms that can identify both genetic variation and DNA methylation from the same sequencing data, with applications in biomedical research and detection of diseases such as cancer.

Understanding how inherited and acquired mutations interact to affect cancer

Germline and somatic variants in the p53 pathway cooperate to influence cancer risk, progression and response to therapy.

Celebrating 100 years of women in Oxford Medical Sciences

Ludwig Oxford Director Professor Xin Lu features in this showcase of women in diverse roles across Oxford’s Medical Sciences Division.

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