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Funding success for Ludwig Oxford early career researchers

Drs Michael McClellan, Marketa Tomkova and Yurena Vivas-Garcia win CRUK Oxford Centre Development Fund awards to pump-prime their research.

Uncovering roles for ubiquitin ligases

Mapping the protein-protein interactions of ubiquitin ligases in the endoplasmic reticulum has revealed a new complex that modulates innate immune signalling.

Linking cancer risk and anthropometric traits

Heritable variants in common cancer genes link anthropometric features like height with cancer risk.

Ludwig Oxford welcomes cancer epigenetics researcher Yang Shi

Yang Shi has been appointed a Member of the Ludwig Oxford Branch to continue his research into chromatin, RNA modifications and cancer.

Insights into the two faces of AMPK, a key nutrient sensor

Professor Colin Goding and colleagues reveal that a distinct metabolic environment in colon cancer cells allows AMPK to be activated by glucose to drive cancer proliferation, with implications for AMPK-targeting cancer drugs.

Expression of interest: Group leader in Cancer Epigenetics

Jobs

Register your interest by 1st September 2020.

Vacancy: Postdoctoral Scientist in Hypoxia Biology

Jobs

Grade 7: £32,817 - £40,322 per annum with discretionary range to £44,045

Debunking assumptions

Researchers from Colin Goding’s lab demonstrate that weakening a transcription factor’s DNA binding affinity in vitro paradoxically increases its function in vivo.

Dr Benjamin Schuster-Böckler elected as a Fellow of Parks College

Ludwig Oxford’s Benjamin Schuster-Böckler is one of 31 Official Fellows in this new Oxford college.

Ludwig Oxford-developed DNA methylation technology forms the basis of new startup company

Biotechnology company, Base Genomics, has launched based on Dr Chunxiao Song’s innovative TAPS technology.

Funding for COVID-19 research

Dr Francesco Boccellato is awarded money from Oxford’s COVID-19 Research Response Fund

Ludwig Oxford technology holds great promise for a multi-cancer blood test

Ongoing Oxford research aims to improve the sensitivity of cancer blood tests with the goal of earlier detection for a variety of cancers.

Professor Sir Peter Ratcliffe elected as an AACR Academy Fellow

Sir Peter joins the ranks of the American Association for Cancer Research’s finest scientists.

Prof Xin Lu honoured by the Royal Society

Ludwig Oxford Branch Director Xin Lu has been elected as a Fellow of the Royal Society for her contributions to cancer biology.

Investigating the genetic risk of adrenocortical carcinoma

Bond lab researchers study the genetic factors associated with the age-dependent incidence of adrenocortical carcinoma.

Adaptation of TAPS for long-read DNA methylation and hydroxymethylation sequencing

Chunxiao Song’s technology can now be used to measure DNA modifications on much longer sections of DNA.

Crowd-sourcing approach to improve endoscopic detection of cancer

Evaluating the algorithms developed to detect a range of imaging artefacts in endoscopy.

Peter Ratcliffe’s Life Scientific

Nobel Prize winner Professor Sir Peter Ratcliffe talks to Jim Al-Khalili on BBC Radio 4.

Anti-cancer HIF-2 inhibition affects the hypoxic ventilatory response

Researchers from Dr Tammie Bishop’s and Prof Sir Peter Ratcliffe’s laboratories show that an anti-cancer HIF inhibitor impairs the normal ventilatory response to low oxygen.

Curbing a cancer-causing pathogen

Ludo Buti and colleagues in Xin Lu’s research group find a path that could reduce colonisation of human stomach cells by the cancer-causing bacteria, Helicobacter pylori.

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