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Publications

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression.

Finisguerra V. et al, (2023), Journal for immunotherapy of cancer, 11

DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition.

Binet R. et al, (2023), bioRxiv

Dynamic fibronectin assembly and remodeling by leader neural crest cells prevents jamming in collective cell migration

Martinson WD. et al, (2023), eLife, 12

Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer.

Naulaerts S. et al, (2023), Sci Transl Med, 15

Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models.

Liao W. et al, (2023), Lancet Respir Med

A target-cell limited model can reproduce influenza infection dynamics in hosts with differing immune responses

Sachak-Patwa R. et al, (2023), Journal of Theoretical Biology, 111491 - 111491

Fusion of colour contrasted images for early detection of oesophageal squamous cell dysplasia from endoscopic videos in real time

Gao XW. et al, (2023), Information Fusion, 92, 64 - 79

Modular Oxidation of Cytosine Modifications and Their Application in Direct and Quantitative Sequencing of 5-Hydroxymethylcytosine.

Xu H. et al, (2023), Journal of the American Chemical Society, 145, 7095 - 7100

Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma

Lafleur VN. et al, (2023), Life Science Alliance, 6, e202201756 - e202201756

Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development.

Ahmed IU. et al, (2023), Bull Math Biol, 85

Minimal Morphoelastic Models of Solid Tumour Spheroids: A Tutorial.

Walker BJ. et al, (2023), Bull Math Biol, 85

Quantification of spatial and phenotypic heterogeneity in an agent-based model of tumour-macrophage interactions

Bull JA. and Byrne HM., (2023), PLOS Computational Biology, 19, e1010994 - e1010994

A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages

Chambers KL. et al, (2023), Mathematical Biosciences, 357, 108971 - 108971

An adverse tumor-protective effect of IDO1 inhibition.

Kenski JCN. et al, (2023), Cell Rep Med, 4

Transcription Factors Regulating Vasculogenesis and Angiogenesis.

Payne S. et al, (2023), Dev Dyn

A multi-centre polyp detection and segmentation dataset for generalisability assessment.

Ali S. et al, (2023), Sci Data, 10

Regulation of immunological tolerance by the p53-inhibitor iASPP.

Akama-Garren EH. et al, (2023), Cell Death Dis, 14

RNA m6A methylation across the transcriptome.

Sendinc E. and Shi Y., (2023), Mol Cell, 83, 428 - 441

Statistical and topological summaries aid disease detection for segmented retinal vascular images

Nardini JT. et al, (2023), Microcirculation

AMPK phosphorylates ZDHHC13 to increase MC1R activity and suppress melanomagenesis.

Sun Y. et al, (2023), Cancer Res

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