Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A
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Impact of Long-Term Chemotherapy on Outcomes in Pancreatic Ductal Adenocarcinoma: A Real-World UK Multi-Centre Study
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Characterising the Behaviour of a Structured PDE Model of the Cell Cycle in Contrast to a Corresponding ODE System.
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Early mucosal responses following a randomised controlled human inhaled infection with attenuated Mycobacterium bovis BCG
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Mouse liver assembloids model periportal architecture and biliary fibrosis
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A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.
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Corrigendum to 'TBX3 Promotes Melanoma Migration by Transcriptional Activation of ID1, which Prevents Activation of E-Cadherin by MITF' Journal of Investigative Dermatology, Volume 141, Issue 9, September 2021, Pages 2250-2260.
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Delineating Mpl-dependent and -independent phenotypes of Jak2 V617F- positive MPNs in vivo.
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Discovery of an LSD1 PROTAC degrader.
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Synergies between Clinicians, Academia and Industry in the Age of AI
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Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation
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20 years of histone lysine demethylases: From discovery to the clinic and beyond.
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Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation.
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Exercise Improves Myocardial Deformation But Not Cardiac Structure in Preterm-Born Adults: A Randomized Clinical Trial.
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Fatty acid uptake activates an AXL-CAV1-β-catenin axis to drive melanoma progression.
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Genetically distinct within-host subpopulations of hepatitis C virus persist after Direct-Acting Antiviral treatment failure
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Isorhamnetin exerts anti-proliferative effect on cancer-associated fibroblasts by inducing cell cycle arrest
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MSP-tracker: A versatile vesicle tracking software tool used to reveal the spatial control of polarized secretion in Drosophila epithelial cells.
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Reticulin-Free Quantitation of Bone Marrow Fibrosis in MPNs: Utility and Applications.
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