Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Goding group

Professor Colin Goding

Our interests lie in understanding how phenotypic heterogeneity is generated within cancer, and the molecular mechanisms that drive three major barriers to effective therapy: microenvironment-driven metastatic spread, dormancy, and phenotypic drug-resistance. Our long-term aim is to develop effective therapies for cancer that take phenotypic heterogeneity into account.

Primarily using melanoma as a model, our work is focussed on the complex interplay between signalling and transcription that underpins the gene expression programs to determine specific cell identities. We use molecular and cellular biology, as well as genome-wide approaches and bioinformatics to address these key issues through a highly collaborative research program that engages with many other laboratories within Oxford and worldwide.

 

Find out more about research in the Goding lab.

Our team