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Professor Colin Goding and colleagues reveal that a distinct metabolic environment in colon cancer cells allows AMPK to be activated by glucose to drive cancer proliferation, with implications for AMPK-targeting cancer drugs.
The double-edged nature of antibody bivalency: mathematical and experimental analysis of cell surface antigen occupancy and opsonization
Journal article
Heirene L. et al, (2026), mAbs, 18
Image-based consensus molecular subtypes and colon cancer recurrence: Understanding the impact of lifestyle factors across subtypes of colon cancer
Journal article
Wesselink E. et al, (2026), Cancer Epidemiology, 103
The embryonic origins of site-specific arthritis
Journal article
Davidson S. et al, (2026), Nature Immunology
The development of a pan-genotypic T cell vaccine against hepatitis C virus using heterologous prime-boost strategies
Journal article
Strain R. et al, (2026), Hepatology, 83, 1540 - 1556
Hypoxia differentially affects coronary vessel formation during heart development.
Journal article
Payne S. et al, (2026), Cardiovascular research
The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia
Journal article
Ling RE. et al, (2026), Blood Journal
Exploring the relationship between vascular remodelling and tumour growth using agent-based modelling
Journal article
Fan N. et al, (2026), PLOS Computational Biology, 22, e1012967 - e1012967
T-World Virtual Human Cardiomyocyte. I. Development, Validation, and Cell Arrhythmogenesis
Journal article
Tomek J. et al, (2026), Circulation Research, 138
Economic evaluation of alternative hepatitis C treatment options: a post hoc analysis of the VIETNARMS trial
Journal article
Turner HC. et al, (2026), eClinicalMedicine, 95, 103969 - 103969
Microbiology Leaders Evolving and Accountable to Progress (MicroBio-LEAP) project: educating, training, and inspiring leaders within the microbial sciences.
Journal article
Bonilla CY. et al, (2026), Journal of microbiology & biology education
m6A modification suppresses innate anti-tumour immunity in colorectal cancer by limiting alu-derived dsRNA accumulation.
Journal article
Wang Y. et al, (2026), Nature communications
Accuracy of Diagnosis in Myeloproliferative Neoplasms With Splanchnic Vein Thrombosis (MPN-SVT).
Journal article
Sreedhar BR. et al, (2026), American journal of hematology
The caspase 11/gasdermin D pathway is a key driver of stress-induced neuroinflammation and behavioral dysfunction in rats.
Journal article
Tiwari S. et al, (2026), Neurochemistry international, 195
Real-world treatment patterns and outcomes in accelerated and blast-phase myeloproliferative neoplasms: Insights from a large multi-centre cohort analysis in the United Kingdom.
Journal article
Rampotas A. et al, (2026), British journal of haematology
Prolyl hydroxylase-dependent proteolysis enables the orthogonal hypoxia responses in plants
Journal article
Shukla V. et al, (2026), Nature Communications, 17
Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF
Journal article
Ma B. et al, (2026), Science Immunology, 11
Toward Integration of Molecular Measures and Artificial Intelligence-Based Assessments With Clinical End Points in Inflammatory Bowel Disease
Journal article
Reinisch W. et al, (2026), Gastroenterology, 170, 686 - 703
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
Journal article
Cruz EM. et al, (2026), Advanced Science, 13
Mutant calreticulin-Cancer driver and Achilles' heel for ET?
Journal article
Reichert M. and Psaila B., (2026), HemaSphere, 10