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Research published in the journal Science by Ludwig Oxford’s Pedro Moura Alves and Max Planck’s Stefan Kaufmann gives insights into the relationship between bacterial pathogens and the host organism during an infection.
Human DNA polymerase ε found to be a source of some of the most prevalent mutations in human cancers and genetic diseases
Kriaucionis Schuster-Böckler Tomkova
10 October 2024
The Kriaucionis, Schuster-Boeckler and Tomkova groups show that DNA polymerase ε makes errors when replicating methylated CpGs, producing C>T mutations at CpG dinucleotides.
Cancer vaccination uncovers novel characteristics of a well-known tumour antigen and mediates anti tumour immunity in new settings
Van den Eynde
9 October 2024
The Van den Eynde group identify a new CD8+ T-cell epitope of the MAGE-type P1A tumour antigen presented in a widely-used tumour model, opening new perspectives for mechanistic studies looking at MAGE-type specific anti-tumour immunity.
Pseudouridine landscape across the human transcriptome mapped by Ludwig Oxford Researchers
Kriaucionis Schuster-Böckler Song
30 September 2024
The Song group at Ludwig Oxford publish a technique for mapping the pseudouridine landscape across the human transcriptome in Nature Methods.
Inflammation stimulates the secretion of antimicrobial peptides in the mucus to promote epithelial defence
Boccellato
18 September 2024
The Boccellato group studied the regulation of antimicrobial peptide secretion in the mucus and its role in determining the colonization of H. pylori, a pathogen associated with stomach cancer.
Adoptive T cell therapy with PHD2/3-deficient CD8 T cells shows an enhanced tumour response
Van den Eynde
6 September 2024
The Van den Eynde group demonstrate that deletion of PHD2/3 enzymes in CD8 T cells show an enhanced tumour response in various cancer models
Vacancies: assistant or associate professor level cancer researchers
Jobs
29 August 2024
The University of Oxford and the Ludwig Institute for Cancer Research are adding to our growing group of cancer researchers. We are seeking individuals at early to mid-stage career stages (Assistant or Associate Professor level).
Oxygen chemosensitivity in chromaffin cells programmed by HIF-2α
Ratcliffe
14 August 2024
Members of the Ratcliffe research group (Maria Prange-Barczynska, Holly Jones and Yoichiro Sugimoto) show that activation of HIF-2α is sufficient to confer oxygen chemosensitivity in chromaffin cells.
Silver LEAF award retained by Ludwig Oxford labs
31 July 2024
Laboratories at Ludwig Oxford have been re-awarded their silver certificate for sustainability by the Laboratory Efficiency Assessment Framework (LEAF)
Ludwig Oxford and IDRM host 6th form students for a taster week of research
Mehdipour Public Engagement Shi Van den Eynde White
22 July 2024
Staff and students at Ludwig Oxford and the Institute of Developmental and Regenerative Medicine put on lectures, panel sessions, lab workshops and more for 6th form students with a keen interest in scientific research.
Ludwig Oxford's Richard White considers cancer and wandering in the woods
Public Engagement White
5 July 2024
Richard White talks to Oxford Sparks producer Charlotte Bird about cancer, and attempting to find cures in the most unlikely places.
Protein Stability may be defined by N-terminal cysteine acetylation and oxidation patterns
Ratcliffe
3 July 2024
The Ratcliffe group investigate the relationship between ADO-catalysed oxidation and NatA-catalysed acetylation of a broad range of protein sequences with N-terminal cysteines. This relationship has implications for O2-dependent protein stability and the hypoxic response.
Professor Yang Shi honoured by the Royal Society
Shi
16 May 2024
Ludwig Oxford Professor Yang Shi has been elected as a Fellow of the Royal Society for his contributions to epigenetics research
Yang Shi elected member of the National Academy of Sciences
Shi
1 May 2024
We are pleased to announce that Oxford Professor of Epigenetics Yang Shi has been elected as a member of the National Academy of Sciences in the United States.
Ludwig Oxford looks back at Melanoma research in the Branch for Skin Cancer Awareness Month
Goding White
1 May 2024
In May, Skin Cancer Awareness Month, Ludwig Oxford looks at recent research into Melanoma from Professors Richard White and Colin Goding
Ludwig Oxford at 2024 AACR
Lu Ratcliffe Schuster-Böckler Van den Eynde White
17 April 2024
Ludwig Oxford staff and students alike share their research in San Diego at the 2024 AACR Annual Meeting
Francesco Boccellato receives esteemed Lee Placito Research Fellowship
Boccellato
8 April 2024
Ludwig Oxford’s Francesco Boccellato has received the prestigious Lee Placito Research Fellowship in Gastrointestinal Cancer.
Ludwig Oxford’s Marketa Tomkova is the first recipient of the Czexpats in Science Award
Tomkova
5 April 2024
Ludwig Oxford’s Marketa Tomkova has been awarded the very first Czexpats in Science Award for her success in the field of genomics and DNA sequencing
Early events following von Hippel Lindau inactivation shape the trajectory of cancer initiation in the kidney
22 March 2024
Work from the Ratcliffe research group demonstrates the early events defining the cell-type specificity of oncogenesis, providing a focus for mechanistic understanding and therapeutic targeting.
Ludwig Oxford’s Helen Byrne recognised as an Honorary Doctor at Chalmers 2024
Byrne
18 March 2024
Ludwig Oxford’s Helen Byrne has been recognised for her contributions and major efforts in the field of mathematical biology
Ludwig Oxford enjoys time at Abingdon ATOM Festival of Science and Technology
Public Engagement
18 March 2024
Ludwig Oxford volunteers head to Abingdon ATOM Festival to run a stall discussing genetic mutation and cancer detection