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Grade 6: £32,332 - £38,205 with a discretionary range to £41,732 per annum

We are seeking to appoint a highly motivated Research Assistant to join our team in The Ludwig Clinical Research Programme at the Nuffield Department of Medicine.

You will work for a team to develop/modify sequencing related technologies, which will be applied to experimental and clinical samples as well as performing techniques which probe chromatin function with a goal to reveal chromatin alterations in cancer.

You will be responsible for managing your own research and administrative activities, within guidelines provided by senior colleagues, while participating in the Ludwig Cancer Research funded clinical research programme line managed by Prof. Skirmantas Kriaucionis. You will be tasked with operating laboratory equipment used for all aspects of cell/molecular biology/biochemistry as well as, determining the most appropriate methodologies to test hypotheses and identify suitable alternatives if technical problems arise.

It is essential that you hold a degree in in biochemistry, molecular biology, chemistry or related subject together with demonstrable experience with molecular biology or biochemistry techniques. You will have sufficient knowledge in biochemical assay optimisation, quality control or automation and will have excellent communication skills, including the ability to present data in written and verbal forms. Among your skills, you will be highly organised with excellent attention to detail, and the ability to handle precious clinical samples, manage a varied workload under pressure and meet deadlines.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract for 3 years and is funded by the Department. Only applications received before 12 midday on Monday 26 February 2024 will be considered. Please quote 170698 on all correspondence.

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The Kriaucionis, Schuster-Boeckler and Tomkova groups show that DNA polymerase ε makes errors when replicating methylated CpGs, producing C>T mutations at CpG dinucleotides.