A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory
Swadling L., Capone S., Antrobus RD., Brown A., Richardson R., Newell EW., Halliday J., Kelly C., Bowen D., Fergusson J., Kurioka A., Ammendola V., Del Sorbo M., Grazioli F., Esposito ML., Siani L., Traboni C., Hill A., Colloca S., Davis M., Nicosia A., Cortese R., Folgori A., Klenerman P., Barnes E.
A prime-boost HCV vaccine strategy induces durable and broad T cell responses, characteristic of those associated with viral control.