Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

In the past five years, significant progress has been made in preparation of various molecularly imprinted polymer (MIP)-based materials for applications in bioassays and biotransformation. This chapter reviews the important advances in these two fields. The first part mainly focuses on the development of various MIP-based bioassays that convert the rebinding of template to the imprinted cavities into measurable luminescent signals, including fluorescence, phosphorescence, Raman scattering, diffraction, and the like. In addition, MIP-based bioassays that are measured by surface plasmon resonance or quartz crystal microbalance are also discussed. In the following part, representative biotransformation reactions that make use of MIPs are summarized. In the last part of this chapter, some remaining challenges are briefly discussed for further development of the two fields.

Original publication





Publication Date





207 - 226


Beijing National Laboratory for Molecular Sciences, MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.


Polymers, Luminescent Measurements, Surface Plasmon Resonance, Biotransformation, Molecular Imprinting, Quartz Crystal Microbalance Techniques