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Publications

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.

Carroll TM. et al, (2023), Cancer cell, 41, 1222 - 1241.e7

Disparities in care and outcomes for primary liver cancer in England during 2008-2018: a cohort study of 8.52 million primary care population using the QResearch database.

Liao W. et al, (2023), EClinicalMedicine, 59

Cell-free DNA TAPS provides multimodal information for early cancer detection.

Siejka-Zielińska P. et al, (2021), Science advances, 7

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution

Louphrasitthiphol P. et al, (2020), Molecular Cell, 79, 472 - 487.e10

Cytosine Methylation Affects the Mutability of Neighboring Nucleotides in Germline and Soma

Kusmartsev V. et al, (2020), Genetics, 214, 809 - 823

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution.

Liu Y. et al, (2019), Nature biotechnology, 37, 424 - 429

BEARscc determines robustness of single-cell clusters using simulated technical replicates

Severson DT. et al, (2018), Nature Communications, 9

Mutational signature distribution varies with DNA replication timing and strand asymmetry

Tomkova M. et al, (2018), Genome Biology, 19

Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands

Owen RP. et al, (2018), Nature Communications, 9

The effects of mutational processes and selection on driver mutations across cancer types

Temko D. et al, (2018), Nature Communications, 9

DNA Modifications: Naturally More Error Prone?

Tomkova M. and Schuster-Böckler B., (2018), Trends in Genetics, 34, 627 - 638

Erratum to “DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine”[DNA Repair, 62 (2018) 1–7]

Tomkova M. et al, (2018), DNA Repair, 65, 79 - 79

DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine

Tomkova M. et al, (2018), DNA Repair, 62, 1 - 7

Cancer Genetics May Aid Diagnostics of Developmental Disorders

Zak J. et al, (2016), Human Mutation, 37, 989 - 989

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

Bardella C. et al, (2016), Cancer Cell, 30, 578 - 594

5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA

Tomkova M. et al, (2016), eLife, 5

The importance of p53 pathway genetics in inherited and somatic cancer genomes

Stracquadanio G. et al, (2016), Nature Reviews Cancer, 16, 251 - 265

Chromatin organization is a major influence on regional mutation rates in human cancer cells

Schuster-Böckler B. and Lehner B., (2012), Nature, 488, 504 - 507

Dosage Sensitivity Shapes the Evolution of Copy-Number Varied Regions

Schuster-Böckler B. et al, (2010), PLoS ONE, 5, e9474 - e9474

Large-scale screening for novel low-affinity extracellular protein interactions

Bushell KM. et al, (2008), Genome Research, 18, 622 - 630

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