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Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase.

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Kozlova A. et al, (2021), Journal of medicinal chemistry, 64, 10967 - 10980

Arid5a: A Missing Link between EMT and Tumoral Immune Resistance

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Van den Eynde BJ., (2021), Cancer Immunology Research

Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase

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Klaessens S. et al, (2021), Proceedings of the National Academy of Sciences, 118, e2022447118 - e2022447118

IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines.

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Levy T. et al, (2021), Bioorganic & medicinal chemistry letters, 40

TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism

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Canè S. et al, (2021), Journal for ImmunoTherapy of Cancer, 9, e001798 - e001798

Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins

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Abi Habib J. et al, (2020), Scientific Reports, 10

NO• /RUNX3/kynurenine metabolic signaling enhances disease aggressiveness in pancreatic cancer.

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Wang L. et al, (2020), International journal of cancer, 146, 3160 - 3169

Preclinical murine tumor models: a structural and functional perspective

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Guerin MV. et al, (2020), eLife, 9

Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors

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Schramme F. et al, (2020), Cancer Immunology Research, 8, 32 - 45

Is There a Clinical Future for IDO1 Inhibitors After the Failure of Epacadostat in Melanoma?

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Van den Eynde BJ. et al, (2020), ANNUAL REVIEW OF CANCER BIOLOGY, VOL 4, 4, 241 - 256

Production of spliced peptides by the proteasome

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Vigneron N. et al, (2019), Molecular Immunology, 113, 93 - 102

Influenza A Virus Infection Induces Viral and Cellular Defective Ribosomal Products Encoded by Alternative Reading Frames

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Zanker DJ. et al, (2019), The Journal of Immunology, 202, 3370 - 3380

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

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Zhu J. et al, (2019), Cancer Immunology, Immunotherapy, 68, 835 - 847

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