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Publications

Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.

Ma J. et al, (2024), Proceedings of the National Academy of Sciences of the United States of America, 121

p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer

Miller P. et al, (2023), Cell Death & Differentiation, 30, 1619 - 1635

Regulation of immunological tolerance by the p53-inhibitor iASPP

Akama-Garren EH. et al, (2023), Cell Death & Disease, 14

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis

Royer C. et al, (2022), Nature Communications, 13

Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders

Dedeić Z. et al, (2018), Cell Death & Differentiation, 25, 1289 - 1303

ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome

Zak J. et al, (2016), Cell Death & Differentiation, 23, 1973 - 1984

Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB

Hu Y. et al, (2015), Oncotarget, 6, 42478 - 42490

Phosphorylation of ASPP2 by RAS/MAPK Pathway Is Critical for Its Full Pro-Apoptotic Function

Godin-Heymann N. et al, (2013), PLoS ONE, 8, e82022 - e82022

Requirement for phosphorylation of P53 at Ser312 in suppression of chemical carcinogenesis

Slee EA. and Lu X., (2013), Scientific Reports, 3

In the right place at the right time: Analysis of p53 serine 312 phosphorylation in vivo

Slee EA. and Lu X., (2011), Cell Cycle, 10, 1345 - 1346

Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo

Slee EA. et al, (2010), Proceedings of the National Academy of Sciences, 107, 19479 - 19484

RPLC-Ion-Trap-FTMS Method for Lipid Profiling of Plasma: Method Validation and Application to p53 Mutant Mouse Model

Hu C. et al, (2008), Journal of Proteome Research, 7, 4982 - 4991

A complex barcode underlies the heterogeneous response of p53 to stress

Murray-Zmijewski F. et al, (2008), Nature Reviews Molecular Cell Biology, 9, 702 - 712

ASPP2: A Gene that Controls Life and Death in Vivo

Vives V. et al, (2006), Cell Cycle, 5, 2187 - 2190

ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth

Vives V. et al, (2006), Genes & Development, 20, 1262 - 1267

The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization

Slee EA. et al, (2004), Oncogene, 23, 9007 - 9016

To die or not to die: how does p53 decide?

Slee EA. et al, (2004), Oncogene, 23, 2809 - 2818

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

Slee EA. et al, (2001), The Journal of biological chemistry, 276, 7320 - 7326

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release.

Slee EA. et al, (2000), Cell death and differentiation, 7, 556 - 565

The viral nucleocapsid protein of transmissible gastroenteritis coronavirus (TGEV) is cleaved by caspase-6 and -7 during TGEV-induced apoptosis.

Eléouët JF. et al, (2000), Journal of virology, 74, 3975 - 3983

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