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Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6

Journal article

Cockman ME. et al, (2022), Proceedings of the National Academy of Sciences, 119

Harveian Oration 2020: Elucidation of molecular oxygen sensing mechanisms in human cells: implications for medicine.

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Ratcliffe PJ., (2022), Clinical medicine (London, England), 22, 23 - 33

Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.

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Eckardt L. et al, (2021), Endocrine-related cancer, 28, 757 - 772

The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes.

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Ortmann BM. et al, (2021), Nature genetics, 53, 1022 - 1035

Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia

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Jatho A. et al, (2021), Circulation Research, 128, 1208 - 1210

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

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Wing PAC. et al, (2021), Cell Reports, 35, 109020 - 109020

Endothelial Oxygen Sensing in Alveolar Maintenance.

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Hodson E. and Ratcliffe P., (2020), American journal of respiratory and critical care medicine, 202, 917 - 919

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

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Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251

Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4

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Bishop T. and Ratcliffe PJ., (2020), Science Signaling, 13

Mechanisms of hypoxia signalling: new implications for nephrology

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Schödel J. and Ratcliffe PJ., (2019), Nature Reviews Nephrology, 15, 641 - 659

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

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Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

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Masson N. et al, (2019), Science, 365, 65 - 69

Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

Journal article

Markolovic S. et al, (2018), Nature Chemical Biology, 14, 988 - 988

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