Increased RhoA pathway activation downstream of αIIbβ3/SRC contributes to heterozygous Bernard Soulier syndrome.
Lordier L. et al, (2025), Haematologica
LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode.
Mazhari Dorooee D. et al, (2025), Angewandte Chemie (International ed. in English)
Oxazolidinone antibiotics impair <i>ex vivo</i> megakaryocyte differentiation from hematopoietic progenitor cells and their maturation into platelets.
Milosevic TV. et al, (2024), Antimicrobial agents and chemotherapy, 68
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection.
Marchal A. et al, (2024), HGG advances, 5
Novel germline JAK2R715T mutation causing PV-like erythrocytosis in 3 generations. Amelioration by Ropeg-Interferon.
Song J. et al, (2024), American journal of hematology
Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Matuozzo D. et al, (2024), Genome medicine, 16
Translating radiological research into practice-from discovery to clinical impact.
Smits M. et al, (2024), Insights into imaging, 15
Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A.
Brierley CK. et al, (2023), bioRxiv
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs.
Bastard P. et al, (2023), Science immunology, 8
Molecular pathogenesis of myeloproliferative neoplasms: Where do we stand in 2023?
Havelange V. and Constantinescu SN., (2023), American journal of hematology, 98, 1512 - 1516
Modulation of Human Thrombopoietin Receptor Conformations Uncouples JAK2 V617F-Driven From Cytokine-Induced Activation.
Papadopoulos N. et al, (2023), Blood
Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology.
Suelves N. et al, (2023), Acta neuropathologica communications, 11
Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation.
Papadopoulos N. et al, (2023), Nature communications, 14
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Matuozzo D. et al, (2023), Genome medicine, 15
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice.
Willekens C. et al, (2023), Leukemia
Innovations 2022 in the field of hemostasis-thrombosis
Bailly S. et al, (2023), Louvain Medical, 142, 101 - 108
Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms.
Pecquet C. et al, (2023), Blood, 141, 917 - 929
Therapeutic activity of GARP:TGF-β1 blockade in murine primary myelofibrosis.
Lecomte S. et al, (2023), Blood, 141, 490 - 502
Editorial: Recent advances in molecular and structural endocrinology.
De Meyts P. and Constantinescu SN., (2023), Frontiers in endocrinology, 14