HIF2α: the interface between oxygen-sensing systems in physiology and pathology
Bishop T. and Ratcliffe PJ., (2025), Physiology
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
Wing PAC. et al, (2022), PLOS Pathogens, 18, e1010807 - e1010807
Hypoxic and Pharmacological Activation of HIF Inhibits SARS-CoV-2 Infection of Lung Epithelial Cells
Wing PAC. et al, (2020), SSRN Electronic Journal
Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control
Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251
Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4
Bishop T. and Ratcliffe PJ., (2020), Science Signaling, 13
Systemic silencing of Phd2 causes reversible immune regulatory dysfunction
Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656
PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies
Fielding JW. et al, (2018), The Journal of Physiology, 596, 4393 - 4412
Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2
Hulley PA. et al, (2017), The Journal of Pathology, 242, 322 - 333
Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice
Ratcliffe P. et al, (2016), Hypoxia, 69 - 69
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
Hodson EJ. et al, (2016), The Journal of Physiology, 594, 1179 - 1195
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
Chan MC. et al, (2015), PLOS ONE, 10, e0132004 - e0132004
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
Bishop T. and Ratcliffe PJ., (2015), Circulation Research, 117, 65 - 79
Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice
Livermore S. et al, (2015), 309 - 313
Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
Peter Ratcliffe P. and Bishop T., (2014), Hypoxia, 197 - 197
Benefits and risks of manipulating the HIF hydroxylase pathway in ischemic heart disease
Bishop T. and Ratcliffe PJ., (2013), Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment, 9780857299208, 17 - 25
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
Bishop T. et al, (2013), The Journal of Physiology, 591, 3565 - 3577
Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice
Chen R-L. et al, (2012), The Journal of Physiology, 590, 4079 - 4091