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Publications

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution

Louphrasitthiphol P. et al, (2020), Molecular Cell

ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer.

Liu D. et al, (2020), Cell death & disease, 11

CagA–ASPP2 complex mediates loss of cell polarity and favors H. pylori colonization of human gastric organoids

Buti L. et al, (2020), Proceedings of the National Academy of Sciences, 117, 2645 - 2655

iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.

Chen S. et al, (2019), Proceedings of the National Academy of Sciences of the United States of America, 116, 17470 - 17479

Autophagy inhibition-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis.

Hill C. et al, (2019), Cell death & disease, 10

Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy.

O'Donnell-Luria AH. et al, (2019), American journal of human genetics, 104, 1210 - 1222

Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells

Wang Y. et al, (2019), Autophagy, 15, 886 - 899

Motion sensing superpixels (MOSES) is a systematic computational framework to quantify and discover cellular motion phenotypes.

Zhou FY. et al, (2019), eLife, 8

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis

Ryzhakov G. et al, (2018), Nature Communications, 9

BEARscc determines robustness of single-cell clusters using simulated technical replicates

Severson DT. et al, (2018), Nature Communications, 9

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73

Papaspyropoulos A. et al, (2018), Nature Communications, 9

Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands

Owen RP. et al, (2018), Nature Communications, 9

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively

Wang Y. et al, (2018), Journal of Cell Science, 131, jcs219782 - jcs219782

Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders

Dedeić Z. et al, (2018), Cell Death & Differentiation, 25, 1289 - 1303

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

Yeh T-L. et al, (2017), Chem. Sci., 8, 7651 - 7668

Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma

Falletta P. et al, (2017), Genes & Development, 31, 18 - 33

ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome

Zak J. et al, (2016), Cell Death & Differentiation, 23, 1973 - 1984

Structure–function relationships of human JmjC oxygenases—demethylases versus hydroxylases

Markolovic S. et al, (2016), Current Opinion in Structural Biology, 41, 62 - 72

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

Lu M. et al, (2016), Cancer Cell, 30, 822 - 823

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration

Turnquist C. et al, (2016), Cell Death & Differentiation, 23, 1515 - 1528

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