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Publications

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia.

Zee BM. et al, (2021), iScience, 24

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.

Stielow B. et al, (2021), Science advances, 7

Simultaneous Inhibition of LSD1 and TGFβ Enables Eradication of Poorly Immunogenic Tumors with Anti-PD-1 Treatment.

Sheng W. et al, (2021), Cancer Discov

Nucleotide resolution profiling of m3C RNA modification by HAC-seq

Cui J. et al, (2020), Nucleic Acids Research

METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing

Chen H. et al, (2020), Cell Research, 30, 544 - 547

MeCLICK-Seq, a Substrate-Hijacking and RNA Degradation Strategy for the Study of RNA Methylation

Mikutis S. et al, (2020), ACS Central Science

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

Anastas JN. et al, (2019), Cancer Cell, 36, 528 - 544.e10

PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

Sendinc E. et al, (2019), Molecular Cell, 75, 620 - 630.e9

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

Sheng W. et al, (2018), Cell, 174, 549 - 563.e19

Polycomb-like proteins link the PRC2 complex to CpG islands

Li H. et al, (2017), Nature, 549, 287 - 291

RNA m6A methylation regulates the ultraviolet-induced DNA damage response

Xiang Y. et al, (2017), Nature, 543, 573 - 576

Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex

Shen H. et al, (2016), Cell, 165, 331 - 342

A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation.

Iwase S. et al, (2016), Cell Reports, 14, 1000 - 1009

DNA Methylation on N6-Adenine in C. elegans

Greer EL. et al, (2015), Cell, 161, 868 - 878

A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation

Laurent B. et al, (2015), Molecular Cell, 57, 957 - 970

BS69/ZMYND11 Reads and Connects Histone H3.3 Lysine 36 Trimethylation-Decorated Chromatin to Regulated Pre-mRNA Processing

Guo R. et al, (2014), Molecular Cell, 56, 298 - 310

A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response

Alpatov R. et al, (2014), Cell, 157, 869 - 881

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

Iwase S. et al, (2011), Nature Structural & Molecular Biology, 18, 769 - 776

The histone demethylase UTX enables RB-dependent cell fate control.

Wang JK. et al, (2010), Genes & development, 24, 327 - 332

A histone H3 lysine 27 demethylase regulates animal posterior development

Lan F. et al, (2007), Nature, 449, 689 - 694

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