Cheryl Tan
Post-doctoral Fellow
Research Interests
My current role as a postdoctoral researcher is to create a platform for cardiotoxicity assessment by combining the usage of iPSC-cardiomyocyte with tissue engineering and high throughput imaging techniques. My research would broadly focus on utilising the platform for in vitro disease modelling, cancer drug screening and cardiotoxicity assessments. I am interested in cancer, cardiac and microvascular remodelling in disease states, and I am passionate about generating functional 3D vascularised organoids and microtissues.
I have a multidisciplinary background in cardiovascular medicine, vascular biology and tissue engineering.
Background
I completed my Bachelor of Science (Hons) in Biomedical Sciences and Master of Research in Reproduction and Pregnancy at the University of Manchester from 2012 to 2016. I recently completed my DPhil on Cardiovascular Medicine at the University of Oxford under the supervision of Professor Paul Leeson, Associate Professor Adam Lewandowski and Assistant Professor Mariane Bertagnolli. My DPhil project focused on a unique population of endothelial progenitor cells to investigate underlying mechanisms for cardiovascular disease development in children and young adults of different birth histories and varying blood pressure profiles. As part of my DPhil, I also developed a vascularised cardiac organoid model during my DPhil.
Recent publications
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Circulating neuropeptide Y dynamics and performance during exercise in heart failure patients with contemporary medical and device therapy
Ayagama T. et al, (2025), Experimental Physiology
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Microscale droplet assembly enables biocompatible multifunctional modular iontronics
Zhang Y. et al, (2024), Science, 386, 1024 - 1030
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A microscale soft lithium-ion battery for tissue stimulation
Zhang Y. et al, (2024), Nature Chemical Engineering
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Endothelial Cell Dysfunction and Retinal Arteriolar Narrowing in Young Adults With Elevated Blood Pressure
Tan C. et al, (2024)
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A machine learning-based score for precise echocardiographic assessment of cardiac remodelling in hypertensive young adults.
Alsharqi M. et al, (2023), European heart journal. Imaging methods and practice, 1