My current role as a postdoctoral researcher is to create a platform for cardiotoxicity assessment by combining the usage of iPSC-cardiomyocyte with tissue engineering and high throughput imaging techniques. My research would broadly focus on utilising the platform for in vitro disease modelling, cancer drug screening and cardiotoxicity assessments. I am interested in cancer, cardiac and microvascular remodelling in disease states, and I am passionate about generating functional 3D vascularised organoids and microtissues.
I have a multidisciplinary background in cardiovascular medicine, vascular biology and tissue engineering.
I completed my Bachelor of Science (Hons) in Biomedical Sciences and Master of Research in Reproduction and Pregnancy at the University of Manchester from 2012 to 2016. I recently completed my DPhil on Cardiovascular Medicine at the University of Oxford under the supervision of Professor Paul Leeson, Associate Professor Adam Lewandowski and Assistant Professor Mariane Bertagnolli. My DPhil project focused on a unique population of endothelial progenitor cells to investigate underlying mechanisms for cardiovascular disease development in children and young adults of different birth histories and varying blood pressure profiles. As part of my DPhil, I also developed a vascularised cardiac organoid model during my DPhil.
Aerobic exercise increases brain vessel lumen size and blood flow in young adults with elevated blood pressure. Secondary analysis of the TEPHRA randomized clinical trial
Lapidaire W. et al, (2023), NeuroImage: Clinical, 37, 103337 - 103337
Aerobic Exercise Training Response in Preterm-Born Young Adults with Elevated Blood Pressure and Stage 1 Hypertension: A Randomised Controlled Trial.
Burchert H. et al, (2022), American journal of respiratory and critical care medicine
Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial
Williamson W. et al, (2022), eClinicalMedicine, 48, 101445 - 101445
Postpartum blood pressure self-management following hypertensive pregnancy: protocol of the Physician Optimised Post-partum Hypertension Treatment (POP-HT) trial
Kitt J. et al, (2022), BMJ Open, 12, e051180 - e051180
Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth
Chuaiphichai S. et al, (2021), Hypertension, 78, 1871 - 1884