Emre Aygin

Research interests

Working from an off-site lab in London, my goals are to clone and produce DNA polymerases of interest to allow for further research here at the LICR. Understanding the mechanisms behind the action of polymerases will help elucidate the factors contributing towards oncogenesis. My role is to make use of a variety of specialist laboratory skills developed over the course of my studies to carry out purified protein production, activity assays, experimental analysis, data interpretation, and presentation of results to the Ludwig team.

Background

Prior to working for the Ludwig Institute, I graduated from St George’s University of London with a distinction in my MRes studies. My research focus was investigating DNA polymerase epsilon – the enzyme responsible for leading strand synthesis – in order to understand the mechanism facilitating hypermutation in certain cancers. Before this, my undergraduate research involved the exploration of QDI as a method of high-speed imaging and evaluation of glial tumours.