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Hannah Pook

DPhil Student

Research interests

My research focuses on how epigenetic factors can influence communication between cancer cells and surrounding microenvironmental cells. The tumour microenvironment (TME) has come to the forefront of cancer research in recent years and TME-cancer interactions are now known to contribute to multiple aspects of cancer progression, including invasion and metastasis. While extensive epigenetic remodelling has been shown to be a key change within microenvironmental cells, how this occurs and whether it may be influenced by cellular pathways remains to be determined.

Background

I am a DPhil student with the Cancer Research UK Cancer Science programme, currently taking time out from my medical degree to pursue research. During my undergraduate BA in Medical Sciences I specialised in cancer and genetics, including completing a third year research project on the role of histone reader MLLT1 in triple negative breast cancer. Outside of research I have taken on teaching roles with St. John’s College, including giving tutorials on genetics to first year medical students and my current role as a lecturer in Study Skills.