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Ludwig Cancer Research engages leading scientists and clinicians in an integrated effort to understand and confront the challenge of cancer. The Oxford Branch is based at the University of Oxford and benefits from excellent links with the global Ludwig and local Oxford research communities.

News

Mads Mol Cell review 2017_2

Reviewing ubiquitin regulation

Posted 20/10/2017

Learn about the latest research into how cells use chains of ubiquitin – a small protein regulatory protein – to control innate immune signalling in a new review in Molecular Cell by Ludwig’s Mads Gyrd-Hansen and Matous Hrdinka. Their review focuses on how ubiquitin chains are tightly regulated and the consequences of deregulation in human diseases. Cover design by Graphics By Maria.

Opportunities for group leaders in infection, immunity and tumour immunology

Posted 11/10/2017

Ludwig Cancer Research at the University of Oxford will be seeking to attract outstanding world-class group leaders in the areas of infection, immunity and tumour immunology. Ludwig Cancer Research is a global non-profit research organisation committed to improving the control of cancer through integrated laboratory and clinical research and novel therapeutic strategies based on the emerging understanding of cancer. With stable core funding ...

Recent publications

DNA Extras SCIENTIST, 31 (9), pp. 48-53.

The role of DNA base modifications: Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome Scientist, 31 (9).

Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD). J Cell Sci, 130 (19), pp. 3322-3335. Article

All roads lead to ubiquitin. Cell Death Differ, 24 (7), pp. 1135-1136. Article

Cell scientist to watch - Mads Gyrd-Hansen. J Cell Sci, 130 (12), pp. 1981-1983. Article

New horizons in hypoxia signaling pathways. Exp Cell Res, 356 (2), pp. 116-121. Article

Research

Our researchers are investigating all stages of cancer, from the risk of disease through to new treatment opportunities. Many of the research groups are interested the causes and consequences of differences among cells within a tumour and variability among different tumours. Find out more about the Ludwig research groups.

Seminars

Ludwig Seminars take place in the NDMRB (TDI) Basement Seminar Room. All University members welcome.

Dr Timothy Errington: Improving Openness and Reproducibility of Scientific Research, 24/Oct/2017 14:00

Browse the Ludwig Seminar Series

 

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