Ludwig Cancer Research engages leading scientists and clinicians in an integrated effort to understand and confront the challenge of cancer. The Oxford Branch is based at the University of Oxford and benefits from excellent links with the global Ludwig and local Oxford research communities.
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We have opportunities for DPhil studentships in single cell analysis of DNA modifications, and artificial intelligence. Deadline 28th April.
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In a Q and A in Oncology Times, Ludwig Oxford's Colin Goding discusses the crucial question of why cancer cells move away from the primary tumour and colonise other tissues. This metastasis is a major challenge for effective therapy. The article summarises findings from recent work by the Goding group about translation reprogramming being an evolutionarily conserved mechanism involved in migration and invasivness.
New horizons in hypoxia signaling pathways. Exp Cell Res. Article
Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics. Hypoxia (Auckl), 5, pp. 11-20. Article
Analysis of live cell images: Methods, tools and opportunities. Methods, 115, pp. 65-79. Article
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer. Nat Rev Mol Cell Biol, 18 (4), pp. 246-262. Article
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma. Genes Dev, 31 (1), pp. 18-33. Article
Our researchers are investigating all stages of cancer, from the risk of disease through to new treatment opportunities. Many of the research groups are interested the causes and consequences of differences among cells within a tumour and variability among different tumours. Find out more about the Ludwig research groups.
Ludwig Seminars take place in the NDMRB (TDI) Basement Seminar Room. All University members welcome.
Prof Alec Kimmelman: Identifying metabolic dependencies in pancreatic cancer, 04/May/2017 11:00
Browse the Ludwig Seminar Series