Ludwig Cancer Research engages leading scientists and clinicians in an integrated effort to understand and confront the challenge of cancer. The Oxford Branch is based at the University of Oxford and benefits from excellent links with the global Ludwig and local Oxford research communities.
Professor Sir Peter Ratcliffe has won one of the most prestigious prizes in medicine. The Lasker Awards recognise contributions that have allowed major advances in the understanding, diagnosis, treatment, and prevention of human disease. Professor Ratcliffe shares the award with William Kaelin and Gregg Semenza for their work understanding the mechanisms by which cells sense and signal hypoxia (low oxygen levels), an important component of many human diseases including cancer.
Sandy Douglas from the Jenner Institute features in this Medical Sciences Division podcast on viruses, released to mark World Rabies Day.
Cancer Genetics May Aid Diagnostics of Developmental Disorders. Hum Mutat, 37 (10), pp. 989. Article
Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet, 12 (9), pp. e1006279. Article
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. Mol Cell, 63 (6), pp. 990-1005. Article
Parallel reverse genetic screening in mutant human cells using transcriptomics. Mol Syst Biol, 12 (8), pp. 879. Article
ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome. Cell Death Differ. Article
Our researchers are investigating all stages of cancer, from the risk of disease through to new treatment opportunities. Many of the research groups are interested the causes and consequences of differences among cells within a tumour and variability among different tumours. Find out more about the Ludwig research groups.
Ludwig Seminars take place in the NDMRB (TDI) Basement Seminar Room. All University members welcome.
Dr Patricia Muller: The oncogenic functions of mutant p53 proteins, 27/Oct/2016 11:00
Browse the Ludwig Seminar Series