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Michael McClellan
Post-doctoral Fellow
Mutations, either germline or spontaneous, are the primary cause of all cancers, yet currently there are limited methods that can detect non-clonal mutations. We have developed a technique to plug the gap in our understanding of the origin of mutations at the single molecule level and are currently using it to explore the interplay between polymerase error rate and DNA modification.
Prior to working in Ludwig Cancer Research I completed a PhD at the University of Sussex under the supervision of Professor Michelle West. The project employed ChIP sequencing and gene expression analysis to investigate the host targets of Epstein-Barr virus latent antigens.