Stanley Ng
Senior Laboratory Manager
Professional Services role
I’m the senior laboratory manager for the Ludwig Institute for Cancer Research. I provide operational management for the laboratories, ensuring as smooth and seamless a research environment as possible for the research staff and students. I also have responsibilities for procurement (consumables and service contracts) for the Institute and run tenders as appropriate for capital purchases. I am also the Departmental Safety Officer, Biological Safety Officer and Senior Radiation Protection Supervisor, key safety roles for ensuring that we operate in a safe manner and with due consideration for the environment. I provide advice for general laboratory practices and techniques. I maintain a keen interest in protein purification and method development, mentoring and advising members of the Ludwig on best practise and methodologies in chromatography.
Background
Prior to joining the LICR, I worked for the Structural Genomics Consortium at the University of Oxford for 10 years as their laboratory manager, and before that as a post-doctoral researcher/laboratory engineer in Prof. Udo Oppermann’s group. Before that I worked for Oxford Glycosciences (one of the University of Oxford’s first spin-out companies) for 10 years, holding a variety of production and research roles culminating as a Research Scientist for an Antibody Therapeutics Group. I earned a DPhil from the Nuffield Department of Clinical Medicine in the SGC, with early research on the biochemistry and structural biology of histone demethylases. I hold a Higher National Diploma in Applied Biology (Biotechnology) from the University of the West of England and a NEBOSH National General Certificate in Occupational Health and Safety.
Other roles
I provide advice and support as required to other NDM units on campus, mentoring laboratory managers. I have formed an informal campus working group of all the major laboratory managers and safety officers, where we can meet and share information.
Recent publications
Ribosomal oxygenases are structurally conserved from prokaryotes to humans
Journal article
Chowdhury R. et al, (2014), Nature, 510, 422 - 426
Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor
Journal article
England KS. et al, (2014), MedChemComm, 5, 1879 - 1886
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
Journal article
Hopkinson RJ. et al, (2013), Chemical Science, 4, 3110 - 3110
Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases
Journal article
Rose NR. et al, (2012), Journal of Medicinal Chemistry, 55, 6639 - 6643
Linking of 2‐Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases
Journal article
Woon ECY. et al, (2012), Angewandte Chemie International Edition, 51, 1631 - 1634
