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Ludwig Cancer Research engages leading scientists and clinicians in an integrated effort to understand and confront the challenge of cancer. The Oxford Branch is based at the University of Oxford, UK and benefits from excellent links with the global Ludwig Cancer Research and local Oxford research communities. Hear more about Ludwig Cancer Research and the Oxford Branch in this film made on the Branch's 10th Anniversary in Oxford:

News

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Ludwig Oxford welcomes new group leaders

Posted 08/05/2019

We are delighted to welcome two new group leaders to the Ludwig Institute for Cancer Research, Oxford Branch.  Dr  Francesco Boccellato and Dr  Pedro Moura Alves join us as Leadership Fellows to expand the Branch’s research into infection and cancer.  Both groups leaders previously worked at the Max Planck Institute for Infection Biology in Berlin, Germany.                                                                                     ...

Mads Gyrd-Hansen awarded Wellcome Trust Senior Research Fellowship renewal

Posted 25/04/2019

Congratulations to Ludwig Oxford’s Mads Gyrd-Hansen, whose Senior Research Fellowship has been renewed by the Wellcome Trust. This > £1 million 5 year award will support the continuation of his research into ubiquitin signalling in immune responses. The Gyrd-Hansen group will build on their previous investigations into the enzyme complex, LUBAC, which joins together ubiquitin molecules so that they form linear chains. These chains are important ...

Postdoctoral Research Scientist - Immunology/Infection Biology

Posted 02/05/2019

Grade 7: £32,236 - £39,609 p.a.

Prof Gyrd-Hansen’s research group is seeking an exceptional and motivated postdoctoral scientist with experience in experimental murine models to undertake a project that focusses on the role of the ubiquitin machinery in immune regulation in vivo. Our long-term goal is to identify molecular processes that can be targeted pharmacologically to treat cancer and other inflammation-driven pathologies. You should have previous laboratory experience relevant to the project, including a wide range of experimental methodologies. Applications must be made online by 12.00 noon on 3rd June 2019.

Recent publications

Motion sensing superpixels (MOSES) is a systematic computational framework to quantify and discover cellular motion phenotypes. Elife, 8. Article

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution. Nat Biotechnol, 37 (4), pp. 424-429. Article

BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma. Genes Dev, 33 (5-6), pp. 310-332. Article

Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells. Autophagy, 15 (5), pp. 886-899. Article

Bisulfite-free and base-resolution analysis of 5-methylcytidine and 5-hydroxymethylcytidine in RNA with peroxotungstate. Chem Commun (Camb), 55 (16), pp. 2328-2331. Article

 

Research

Our researchers are investigating all stages of cancer, from the risk of disease through to new treatment opportunities. Many of the research groups are interested in the causes and consequences of differences among cells within a tumour and variability among different tumours. Find out more about the Ludwig research groups.

 

Seminars

Ludwig Seminars take place in the NDMRB (TDI) Basement Seminar Room. All University members welcome.

Dr Maura Gillison: HPV and alterations to the host genome structure and function, 20/May/2019 11:00

Browse the Ludwig Seminar Series

 

 

 

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