Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
Guitart AV., Subramani C., Armesilla-Diaz A., Smith G., Sepulveda C., Gezer D., Vukovic M., Dunn K., Pollard P., Holyoake TL., Enver T., Ratcliffe PJ., Kranc KR.
Key Points Hif-2α–dependent signaling is dispensable for steady-state multilineage hematopoiesis. Hif-2α is not essential for HSC self-renewal.