Contact information
Research groups
Keith Chambers
Post-doctoral Researcher
research interests
In my research I develop mathematical models to increase understanding of biomedical phenomena such as tumour growth and atherosclerosis. Mathematical modelling typically involves first identifying the key biological processes and then expressing them in the language of differential equations, before solving the resulting equations with the help of analytical and computational techniques to gain insight. My particular focus is on the emergence of cell-to-cell variation within a population, which I study using structured differential equation models.
As part of the Byrne group, I am currently working with Profs. Richard White and Colin Goding to develop models to understand how lipids mediate cancer cell plasticity in melanoma.
background
I recently completed my DPhil in Mathematics at the University of Oxford, based at the Wolfson Centre for Mathematical Biology in the Mathematical Institute. My DPhil research focused on the emergence of heterogeneity in early atherosclerotic lesion macrophages, with particular focus on cell-to-cell variation in lipid content, inflammatory phenotype and spatial position. Prior to Oxford, I studied for a BSc. (Advanced Mathematics) (Honours) at the University of Sydney. My honours research also focused on lipid content heterogeneity in early atherosclerosis.