Ruisi Rachel Li

research interests

The cancer genome is developed from the accumulation of newly generated mutations over the lifespan. One of the challenges is the identification of these cancer-driving mutations in the early stages of disease development. In gastric cancers, bile reflux is known to increase the risk of cancer initiation, but the underlying mechanism remain unknown. My research focuses on the characterisation and profiling of genetic mutations in bile exposed gastric cells via computational approaches with hope to elucidate cancer initiating mutational signatures.

background

I obtained my HBSc specialising in Molecular Biology & Biotechnology, minoring in Applied Statistics at the University of Toronto in Canada. In my fourth year, I undertook a research studentship at the Hospital for Sick Children (Canada) working on the deconvolution of rare disease genetics and epigenetic. I then pursued a MSc in Genomic Medicine at the University of Oxford where I conducted my thesis research under the supervision of Professor Schuster-Böckler.