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Control of Wnt signalling by KDM5C during development impacts cognition

Shi

Ludwig Oxford’s Yang Shi’s research team identifies KDM5C as a crucial sentinel for neurodevelopment.

Melanoma Genomic Instability increased by DNA damage remodelling the MITF interactome

Goding

The Goding lab shows that Microphthalmia-associated Transcription Factor (MITF) plays a non-transcriptional role in shaping the DNA Damage Response programmes. MITF is phosphorylated on exposure to DNA damaging agents, and interacts with a DNA repair complex, increasing the level of genomic instability within cells which can have an impact on cancer initiation.

Vacancy: Research Assistant - Sequencing

Jobs Kriaucionis

Grade 6: £32,332 - £38,205 with a discretionary range to £41,732 per annum

Ludwig Oxford celebrates the end of a successful year

Ludwig Oxford meets as a whole to share their science and creativity in talks, posters, writing and art competitions and more for the end of year retreat

Insights made into how Red Hair Colour (RHC) trait variants may increase melanoma risk

Goding

The Goding lab have worked in collaboration with Bill Pavan’s group of the National Human Genome Research Institute, at the National Institutes of Health (NIH), to uncover the transcriptomic profile of MC1R-inhibited melanocytes at single-cell resolution in Pigment Cell & Melanoma Research.

Ludwig Oxford DPhil candidate receives MSD Teaching Excellence Award

Goding

Ludwig Oxford’s Olly Featherstone has been awarded an Early Career Excellent Teacher award by the Medical Sciences Division Teaching Excellence Awards.

New DPhil studentships in Cancer Science available for 2024 intake

Boccellato Byrne Lu Rittscher Schuster-Böckler Tomkova Van den Eynde White

Ludwig Oxford supervised DPhil studentships in Cancer Science are now being advertised for the 2024 intake

Collaboration announced between Satisfai and University of Oxford to develop AI methods of evaluating Barrett's oesophagus

Rittscher

An agreement between Satisfai Health Inc and the University of Oxford will forward the automated assessment of Barrett’s oesophagus, designed to determine patients with the highest risk of developing oesophageal cancer.

Acetylation reprograms MITF target selectivity and residence time

Goding

Ludwig Oxford’s Colin Goding and his lab reveal an acetylation-mediated switch that suppresses differentiation and provides an explanation of why a human K206Q MITF mutation is associated with Waardenburg syndrome.

A role for ASPP2 in Hepatitis C infection

Lu

Ludwig Oxford researchers in the Lu lab uncover new insights into the role of ASPP2 in Hepatitis C virus replication and transmission.

Ludwig Oxford Professor Announced

White

Congratulations to Richard White who has been successful in the 2023 University recognition exercise.

Ludwig Oxford’s Dr Mehdipour in one of three University of Oxford teams shortlisted for Cancer Grand Challenges funding

Mehdipour

Dr Parinaz Mehdipour is a member in one of the 12 teams shortlisted for funding from Cancer Grand Challenges, seeking to understand retrotransposable elements in cancer.

Ludwig Oxford welcomes new Leadership Fellow Dr Marketa Tomkova

Tomkova

Our new Leadership Fellow launches a research group in computational cancer genomics

Ludwig Oxford’s Richard White awarded for his Outstanding Research by the Society for Melanoma Research

White

Richard White has been named for the 2023 Outstanding Research award by the Society for Melanoma Research

Comparative analysis of ADO and PHD enzymes allows researchers to better understand their co-evolution and integration into oxygen homeostasis mechanisms

Ratcliffe

Ludwig Oxford’s Peter Ratcliffe and Tom Keeley have undertaken a comparative analysis of a number of enzymes involved in the adaption of cells to oxygen level changes.

Ludwig Oxford clinical trial shows Immunochemotherapy outcomes predicted by tumour monocyte content

Lu Schuster-Böckler Van den Eynde

An analysis of samples obtained from a uniquely designed window-of-opportunity clinical trial (LUD2015-005) has shown that high tumour monocyte content (TMC) is an unexpected predictor of greater overall survival in inoperable oesophageal adenocarcinoma (OAC) patients.

Ludwig Oxford labs awarded Silver in laboratory sustainability

Laboratories at Ludwig Oxford have been awarded a Silver certificate for sustainability following the Laboratory Efficiency Assessment Framework (LEAF).

p53 inhibitor iASPP acts as a surprise pancreatic cancer suppressor

Lu

Ludwig Oxford’s Xin Lu shows an unexpected suppression of KRAS and inflammation driven pancreatic cancer by the p53 suppressor iASPP.

Hypertension treatment drugs may play a role in boosting clinical immunotherapy

Van den Eynde

Team from the Van den Eynde group have discovered that some molecules previously used to treat hypertension might also help the immune system to better fight cancer cells

Oxford DeLIVER research attracts 1000 patients for innovative Pearl clinical study

Barnes

1000 patients have been recruited for the Pearl study within the DeLIVER programme.

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