New research uncovers the role of Chromosome 21 amplification and DYRK1A overexpression in BP-MPN progression
13 June 2025
Researchers at the University of Oxford have identified a potential new therapeutic target in BP-MPN, a particularly aggressive and hard-to-treat form of leukaemia.
Topological data analysis reveals links between shape and function in new liver organoid model
29 May 2025
Topological data analysis of a next-generation liver organoid model characterises how the shape and morphology of 2D projections of organoids change over time
Vacancy: Laboratory Technician
27 May 2025
Standard Grade 5: Salary in range £31,459 - £36,616 per annum (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
Discovery of a first-in-class LSD1 PROTAC degrader by the Shi lab
16 May 2025
Discovery of a first-in-class LSD1 PROTAC degrader by the Shi lab opens new therapeutic paths for the treatment of AML.
Professor Yang Shi wins 2025 Léopold Griffuel Prize for Fundamental Research
7 May 2025
The ARC Foundation for Cancer Research has recognised Professor Yang Shi’s contributions to the field of cancer epigenetics with the 2025 Léopold Griffuel Prize for Fundamental Research.
St Birinus School support Ludwig Oxford as part of their First Give programme
23 April 2025
Ludwig Oxford Branch are honoured by the support shown by the Year 9 students at St Birinus School Didcot who have won their First Give School Final
A combination approach to inducing differentiation in acute myeloid leukaemia
16 April 2025
A novel combination therapy for acute myeloid leukaemia (AML), developed by the Shi lab, shows therapeutic promise by promoting differentiation of immature blood cells.
Dr Parinaz Mehdipour awarded CRUK Early Detection and Diagnosis Primer Award
28 February 2025
Ludwig Oxford’s Parinaz Mehdipour has been awarded a CRUK Early Detection and Diagnosis Primer to identify circular RNA biomarkers for the early detection of normal colon cell transformation into precancerous and colorectal cancer states
Melanoma progression driven in part by fatty acid uptake
28 February 2025
The Goding lab working in collaboration with the University Rey Juan Carlos show that fatty acid uptake activates an AXL-CAV1-β-catenin axis to drive melanoma invasiveness.
Biomedical Research Career Week back for another year
25 February 2025
The joint program between Ludwig Oxford and the Institute of Developmental & Regenerative Medicine inviting 6th form students to join us for a research-based career week is running again from 7th - 11th July 2025
Chunxiao Song announced as finalist for 2025 UK Blavatnik Awards for Young Scientists
19 February 2025
Chunxiao Song has been announced as one of nine finalists for The 2025 UK Blavatnik Awards for Young Scientists, in the Chemical Sciences division.
Colin Goding presented with Lifetime Achievement Award from Society for Melanoma Research
17 February 2025
Professor Colin Goding has been named as the 2024 Lifetime Achievement Award by the Society for Melanoma Research
Ludwig Oxford and Oxford's Centre for Immuno-Oncology discuss World Cancer Day
4 February 2025
Group leaders and leadership fellows of Ludwig Oxford and the Centre for Immuno-Oncology look at how their current research fits with the World Cancer Day theme 'united by unique'.
Professor Benjamin Schuster-Boeckler elected as a Fellow of the Royal Society of Biology
3 January 2025
Ludwig's Ben Schuster-Boeckler has been announced as a Fellow of the Royal Society of Biology
Ludwig Oxford round up another successful year
17 December 2024
Staff and students at Ludwig Oxford celebrate the end of 2024 with Science, Team Building and Prizes
Production of biocompatible multifunctional modular iontronics enabled by microscale droplet assembly
29 November 2024
The Lu lab collaborates with the École Polytechnique Fédérale de Lausanne and Oxford departments to report the use of surfactant-supported assembly of freestanding microscale hydrogel droplets to construct iontronic modules and biointerfaces.
Suppressing the function of H3K27M mutant histones reduces the drive of incurable paediatric gliomas
25 November 2024
The Shi group have leveraged functional genomics in C. elegans to suppress the function of H3K27M mutant histones, which drive 80% of incurable childhood brain tumours diffuse midline gliomas.
Human DNA polymerase ε found to be a source of some of the most prevalent mutations in human cancers and genetic diseases
10 October 2024
The Kriaucionis, Schuster-Boeckler and Tomkova groups show that DNA polymerase ε makes errors when replicating methylated CpGs, producing C>T mutations at CpG dinucleotides.
Cancer vaccination uncovers novel characteristics of a well-known tumour antigen and mediates anti tumour immunity in new settings
9 October 2024
The Van den Eynde group identify a new CD8+ T-cell epitope of the MAGE-type P1A tumour antigen presented in a widely-used tumour model, opening new perspectives for mechanistic studies looking at MAGE-type specific anti-tumour immunity.
Pseudouridine landscape across the human transcriptome mapped by Ludwig Oxford Researchers
30 September 2024
The Song group at Ludwig Oxford publish a technique for mapping the pseudouridine landscape across the human transcriptome in Nature Methods.